---
alias: user-guide-approve-protocol-instance-dispositions
description: "Manage and approve material dispositions associated with protocol instances within the system"
---

# Approve Protocol Instance Material Dispositions

:lock: ProtocolInstance.**ApproveMaterialsDispositions**

## Overview

This operation is used to manage the applied dispositions to each **Material**.

## Setup

No special setup is required other than to meet the preconditions of the transaction.

## Preconditions

* Protocol instance exists, is active and is in the system state *Open*.
* The new Protocol Instance state must be different from the current Protocol Instance state.
* The new Protocol Instance state belongs to the Protocol Instance State Model.
* If a role is defined in the current Protocol Instance Path State, the user must belong to that role.

## Sequence of Steps

### Step 1

1. Select the **Material Disposition**.
2. Optionally, enter a comment.
3. Click **Approve**.

![Protocol_Approve_Material_Dispositions][Protocol_Approve_Material_Dispositions]

!!! note
	When selecting each of the materials on the left-hand side of the screen, it is possible to see more information on them on the right-hand side of the screen.

[Protocol_Approve_Material_Dispositions]: ../images/Protocol_Approve_Material_Dispositions.png