---
alias: user-guide-execute-protocol-instance-dispositions
description: "This documentation details executing material dispositions within a protocol instance workflow"
---

# Execute Protocol Instance Material Dispositions

:lock: ProtocolInstance.**ExecuteMaterialsDispositions**

## Overview

This operation is used to execute the disposition of a **Material**.

## Setup

No special setup is required other than to meet the preconditions of the transaction.

## Preconditions

* Protocol Instance Material *IsDispositionApproved* must be true.
* Protocol Instance exists, is active and is in the system state *Open*.
* Material exists and is Active.

## Sequence of Steps

### Step 1

1. Select the **Material** to perform the Disposition.
2. Optionally, enter a comment.
3. Click on **Execute**.

![Protocol_Execute_Disposition][Protocol_Execute_Disposition]

[Protocol_Execute_Disposition]: ../images/Protocol_Execute_Disposition.png