---
alias: user-guide-manage-protocol-instance-dispositions
description: "Manage material dispositions associated with protocol instances, ensuring accurate system state updates"
---

# Manage Protocol Instance Material Dispositions

:lock: ProtocolInstance.**ManageMaterialsDispositions**

## Overview

This operation allows you to manage the applied **Dispositions** to each **Material**.

## Setup

No special setup is required other than to meet the preconditions of the transaction.

## Preconditions

* Protocol Instance Material *IsDispositionApproved* must be false.
* Protocol Instance exists, is active and is in system state *Open*.
* Material exists and is Active.

## Sequence of Steps

### Step 1

1. Click on **Manage Dispositions**.
2. Select a **Material** from the list.
3. Select a **Disposition** from the list.
4. Fill in the additional information required, depending on the **Disposition**.
5. Click on **Update** to finalize the process.

![Protocol_Manage__Material_Disposition]

!!! note
	Available dispositions can be managed when the **Protocol** is created.

[Protocol_Manage__Material_Disposition]: ../images/Protocol_Manage__Material_Disposition.png